A SINGLE CELL ATLAS OF FROZEN SHOULDER CAPSULE IDENTIFIES FEATURES ASSOCIATED WITH INFLAMMATORY FIBROSIS RESOLUTION

A single cell atlas of frozen shoulder capsule identifies features associated with inflammatory fibrosis resolution

Abstract Frozen shoulder is a spontaneously self-resolving chronic inflammatory fibrotic human disease, which distinguishes the condition from most Kitchen Utensil Holders fibrotic diseases that are progressive and irreversible.Using single-cell analysis, we identify pro-inflammatory MERTKlowCD48+ macrophages and MERTK + LYVE1 + MRC1+ macrophages e

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An analogue approach to investigate non-fear emotions and working mechanisms in imagery rescripting and imaginal exposure: Preliminary findings

Some studies suggest Imagery Rescripting (ImRs) may be more effective than Imaginal Exposure (IE) for processing trauma when non-fear emotions are predominant.ImRs has been proposed to work through positive memory revaluation and increasing mastery, while IE focuses on fear toleration through inhibitory learning.We present standardized ImRs and IE

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An atlas of robust microbiome associations with phenotypic traits based on large-scale cohorts from two continents.

Numerous human conditions are associated with the microbiome, yet studies are inconsistent as to the magnitude of the associations and the bacteria involved, likely reflecting insufficiently employed sample sizes.Here, we collected diverse phenotypes and gut microbiota from 34,057 individuals from Israel and the U.S.Analyzing these data using a muc

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